Pharmacology for Natural Sciences

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key publications

Key publications

Hennis K, Rötzer RD, Rilling J, Wu Y, Thalhammer SB, Biel M, Wahl-Schott C, Fenske S.
In vivo and ex vivo electrophysiological study of the mouse heart to characterize the cardiac conduction system, including atrial and ventricular vulnerability. Nature Protoc. 2022 May;17(5):1189-1222. doi: 10.1038/s41596-021-00678-z. 2-year Impact Factor: 13.5; 5-year Impact Factor: 12.7

Esfandyari D, Idrissou BMG, Hennis K, Avramopoulos P, Dueck A, El-Battrawy I, Grüter L, Meier MA, Näger AC, Ramanujam D, Dorn T, Meitinger T, Hagl C, Milting H, Borggrefe M, Fenske S, Biel M, Dendorfer A, Sassi Y, Moretti A, Engelhardt S.
MicroRNA-365 regulates human cardiac action potential duration. Nature Commun. 2022 Jan 11;13(1):220. doi: 10.1038/s41467-021-27856-7. 2-year Impact Factor: 14.9; 5-year Impact Factor: 14.1

Fenske S, Hennis K*, Brox VF*, Roetzer R, Becirovic E, Scharr A, Gruner C, Ziegler T, Hammelmann V, Brennan J, Efimov IR, Pauza AG, Moser M, Wotjak CT, Kupatt C, Goenner R, Zong X, Biel M, Wahl-Schott C
cAMP-dependent regulation of HCN4 controls the tonic entrainment process in sinoatrial node pacemaker cells. Nat Commun. 2020 Nov 3;11(1):5555. doi: 10.1038/s41467-020-19304-9.

Böhm S, Splith V, Riedmayr LM, Rötzer RD, Gasparoni G, Nordström KJV, Wagner JE, Hinrichsmeyer KS, Walter J, Wahl-Schott C, Fenske S, Biel M, Michalakis S, and Becirovic E
A gene therapy for inherited blindness using dCas9-VPR-mediated transcriptional activation. Sci Adv. 2020 Aug 19;6(34):eaba5614. doi: 10.1126/sciadv.aba5614. eCollection 2020 Aug.

Chen CC, Cang C, Fenske S, Butz E, Chao YK, Biel M, Ren D, Wahl-Schott C, Grimm C
Patch-clamp technique to characterize ion channels in enlarged individual endolysosomes. Nat Protoc. 2017 Aug;12(8):1639-1658.

Fenske S, Pröbstle R, Auer F, Hassan S, Marks V, Pauza DH, Biel M, Wahl-Schott C
Comprehensive multilevel in vivo and in vitro analysis of heart rate fluctuations in mice by ECG telemetry and electrophysiology. Nat Protoc. 2016 Jan;11(1):61-86.

Fenske S*, Krause S*, Hassan SIH, Becirovic E, Auer F, Bernard R, Kupatt C, Lange P, Ziegler T, Wotjak C, Zhang H, Hammelmann V, Paparizos C, Biel M, Wahl-Schott CA
Sick sinus syndrome in HCN1-deficient mice. Circulation. 2013 Dec 17;128(24):2585-94.

Fenske S, Mader R, Scharr A, Paparizos C, Cao-Ehlker X, Michalakis S, Shaltiel L, Weidinger M, Stieber J, Feil S, Feil R, Hofmann F, Wahl-Schott C, Biel M
HCN3 contributes to the ventricular action potential waveform in the murine heart. Circ Res. 2011 Oct 14;109(9):1015-23.